Read Epigenetic Nutrition©
Explore the available chapters below. While each chapter builds on the previous one, every chapter can also be read as a standalone resource.
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Available Chapters
Introduction
Why early-onset colorectal cancer is increasing—and why prevention research must look beyond detecting visible disease.
Chapter 1: The Colon – A Difficult Environment
Explore why the colon’s dense microbial population, low-oxygen conditions, continual exposure to dietary compounds, and rapid cellular renewal make it a uniquely challenging biological environment.
Chapter 2: Epigenetics – The Colonocyte’s Adaptive Operating System
Explore how DNA methylation, histone modification, chromatin remodeling, and noncoding RNAs help colonocytes adapt to changing metabolic and microbial signals—and how disruption of this regulatory system may contribute to colorectal cancer development.
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Chapter 3: Soluble Fiber
Explore how soluble fiber feeds the colonic microbiome, supports short-chain fatty acid production, and connects diet with colonocyte metabolism and epigenetic regulation.
Chapter 4: Polyphenols
Explore how plant polyphenols are absorbed or transformed by the microbiome into compounds that may influence cellular signaling, inflammation, and epigenetic regulation.
Chapter 5: Fiber and Polyphenol Synergy
Discover how fermentable fiber and polyphenols may work together to shape microbial metabolism, support beneficial metabolite production, and influence the colon’s biological environment.
Chapter 6: Protein – Friend or Foe?
Examine how dietary protein supports health while excess protein reaching the colon may undergo microbial fermentation and generate metabolites with differing effects on colon health.